Ari Afilalo on Jewish Genetic Diseases
There are many Jewish personalities who are settled in the United States. Ari Afilalo is one of them. He belongs to the Sephardic Jewish community and is very close to the pedagogy and laws. In this blog, we will discuss genetic diseases that are common in the Jewish community.
Diseases are common in each and every community or place. But some diseases are genetic diseases, which are passed on through the generations. The autosomal recessive disorder is a rare genetic disease which is common in Jewish people in comparison to the other populations. Autosomal recessive diseases are a rare type of disease that can be transferred from parents to their children without the parents themselves suffering from the disorder. Parents can carry the gene which causes the disorder in the children. There is about a 50 % chance of becoming immune to this type of disorder.
Jews are further divided into smaller categories, such as Ashkenazi Jews, Sephardic and Mizrahi Jews. In Ashkenazi Jews, it is estimated that out of three, one person will carry one of about nineteen genetic diseases. In comparison to other communities, Jews have higher carrier rate for more than 40 genetic diseases. Some commonly known diseases include Cystic Fibrosis, Gaucher disease, Tay-Sachs, Nemaline Myopathy and Walker Warburg disease. Mizrahi and Sephardic Jews also carry some rare disorders.
Some diseases are considered to be more common among Jews because of the founder effect, as genetic diversity is reduced and the population drops to a small number. In addition to that, Jews are often directed to marry only another Jew. This is the reason that the genetic mutations keep being passed to the next generations as they weren’t reduced by the introduction of new genes. There has been a strong decline in genetic diseases since the 1970s. To find out more click here.